Healthcare is and has always been a big part of my life.
My father was a registered pharmacist who owned his own store in Detroit. All of his 3 children started their working years with him. I started working in the drugstore when I was nine as a dishwasher behind the soda fountain.
When I graduated from Wayne State University’s Pharmacy School in 1977, I started working for a small chain of drug stores. I soon became a partner and pharmacy director by the time we sold the company.
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Question from Carol B.:
I have a stent in my LAD and take plavix, isosorbide mono, toprol XL, 325 mg aspirin, simvastatin for the heart regimen.
I also take, synthroid, omeprazole and Wellbutrin XL. I also take furosimide for water retention but don’t do it regularly because
I have a torn meniscus in the left knee, a very painful hammertoe (2nd toe pulling away from the foot joint) and need to take celebrex.
When I did drug interactions on Medscape it warned against taking furosimide and celebrex together.
I need the diuretic and also celebrex. Is it possible to take the furosimide early in the morning and celebrex mid-day?
Thanks.
Clyde’s Response: Hi Carol, Your friend Clyde the Pharmacist
The combination of lasix and celebrex is something I’m not presently familiar with, however, I will investigate the matter and get back to you. Celebrex can cause some fluid retention at higher doses and this can work against the lasix(furosemide). The aspirin and celebrex combination, which for heart patients has some concerns since celebrex should be used with caution in cardiovascular disease. Check with your cardiologist to see if he knows and agrees with the celebrex just to be on the safe side. Also, the aspirin and the celebrex can increase gastrointestinal ulceration since either one by itself can initiate such a problem. It’s best that an enteric coated aspirin be used. Aspirin and plavix are both platelet inhibitors, therefore, watch for excessive bruising. Cuts and scratches may need a little more attention to create coagulation. The aspirin and plavix are standard protocol so don’t worry about the two together, but ask your cardiologist about the 325mg strength. Also, you’re on omeprazole which tells me you have a stomach issue. Lastly, furosemide should be taken in the morning. Celebrex midday is okay, but again check with your heart doctor.
Posted on: Sep 29, 2008
1 comments - Categories:
T wrote on 10/06/08 11:58 AM
Has there ever been any reports or interactions that you are familiar with that show the side affects of taking furosemide? Is one of those reactions (side affects) heightened anxiety or anxiety attacks?